Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
As is the case with nucleoside reverse transcriptase inhibitors (NRTIs), NNRTIs also work by interfering with the transcription of viral DNA during HIV's replication process. However, rather than mimicking nucleotides assimilated in viral DNA, NNRTIs work by directly binding to the reverse transcriptase and inhibiting viral DNA polymerization.
FDA-approved NNRTIs
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*Atripla is a combination tablet that contains 2 NRTIs and an NNRTI.
†The brands listed above are trademarks of their respective owners and are not trademarks of The GlaxoSmithKline Group of Companies. The makers of these brands are not affiliated with and do not endorse GlaxoSmithKline or its products.