Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
NRTIs work by structurally mimicking the nucleotide building blocks that HIV normally uses to generate copies of viral DNA. Once NRTIs are integrated into the growing HIV DNA chain during transcription, the polymerization of viral DNA is discontinued. The result is a dysfunctional copy of viral DNA and disruption of the viral reproduction process.
FDA-approved NRTIs
For additional information about GlaxoSmithKline HIV products, including serious and sometimes fatal hypersensitivity reactions to drugs containing abacavir, please click on "Important Safety Information/Indications."
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*Atripla is a combination tablet that contains 2 NRTIs and an NNRTI.
†The brands listed above are trademarks of their respective owners and are not trademarks of The GlaxoSmithKline Group of Companies. The makers of these brands are not affiliated with and do not endorse GlaxoSmithKline or its products.